Dorofeyeva U
ntroduction: Oocyte donation has been proven to be
a successful treatment option for women who can not
conceive because of advanced age, diminished ovarian
reserve or genetic disease.
Nowadays oocyte donation is an established standard
and effective treatment for age related infertility. However,
legal regulations in each country regarding oocyte
donation are different and due to that fact many patients
had to travel out of home country to receive egg donation
treatment. In recent decade that practice has been
changed. Clinics are offering complete oocyte donation
treatment with the gametes being imported from the
banks or another clinics.
Aims: The purpose of this study is to present a systematic
review of the available results of cross-border transportation
of biological materials and compare it with a standard
approach involved pa-tients travelling. We investigated
results achieved in 23 centers with vitrified / warmed
oocytes and embryos from one center - supplier.
Materials and Methods: All egg donation treatment cycle
results in 23 medical centers during the years 2014-2019
were included. 4 centers performed cycles with embryo
creation in a clinic supplier and 19 received vitrified oocytes.
Results: In an embryo creation programs 596 clinical pregnancies
has been achieved out of 2001 embryotransfers,
which lead to 30% clinical pregnancy rate and very from
28 to 42 %. Cumulative clinical pregnancy is between 79
to 86% depending on a clinic. In clinics with vitrified oocytes
supply 12577 were warmed, with 82% survival rate
(very from 69 to 94%), 76% fertilization rate and 34% (
very from 26 to 58%) CPR rate per cycle.
Conclusions: Results show that, once all critical aspects
are considered, import of biological mate-rials and complex
offer by a clinic have many more benefits for the
patients in terms