Ottavio Di Marco, Carmine Di Marco and Stefania Di Mauro
The co-morbidity between migraine and bipolar disorders is well documented in numerous clinical and epidemiological studies, but the aetiologies are currently unknown. Many Authors have suggested some pathophysiological mechanisms in common. This co-morbidity, moreover, influences the outcome of both disorders. The aim of our work is to describe two case report, whose clinical history appears suggestive of the population subgroup with BD in comorbidity with migraine supposed in literature.